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0 · The genomics of heart failure: design and rationale of the
1 · Study design of Heart failure Events reduction with Remote
2 · Novartis announces positive results from a Phase IV study
3 · Novartis announces Lancet publication of pioneering study in
4 · HERMES: Effects Of Ziltivekimab Versus Placebo On Morbidity
5 · HER
6 · Fremanezumab for the Preventive Treatment of
7 · Erenumab versus topiramate: post hoc efficacy analysis from the
8 · Erenumab versus topiramate for the prevention of migraine
9 · A Controlled Trial of Erenumab for Episodic Migraine
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Background: We compared the tolerability and efficacy of erenumab, a monoclonal antibody binding to the calcitonin gene-related peptide receptor, to topiramate for migraine prophylaxis .
Novartis. The HERMeS trial will assess the efficacy of a TM-based follow-up strategy for rea.
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Basel, November 2, 2020 — Novartis announced today that HER-MES, the first Phase IV, randomized, double-blind, double-dummy, head-to-head study of Aimovig ® (erenumab) .HER-MES is the first randomized, double blind, head-to-head study of Aimovig® (erenumab) against topiramate in patients with episodic and chronic migraine1. KEY CLINICAL TRIAL .
Erenumab administered subcutaneously at a monthly dose of 70 mg or 140 mg significantly reduced migraine frequency, the effects of migraines on daily activities, and the .The HERMES trial is an international, multicentre, parallel group, randomized, double-blind, study in patients with HFpEF and HFmrEF, evaluating the effect of ziltivekimab 15mg compared with . Abstract. Background. Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene–related peptide (CGRP), is being investigated as a preventive treatment for migraine. We compared two.
Conclusions: HERMES is a global collaboration aiming to (i) identify the genetic determinants of heart failure; (ii) generate insights into the causal pathways leading to heart failure and enable .
Novartis. The HERMeS trial will assess the efficacy of a TM-based follow-up strategy for real-world 'vulnerable phase' HF patients combining telemonitoring and teleintervention. The LIBERTY trial is the first study of a CGRP-targeted therapy in a patient population where multiple preventive treatments had previously failed. Patients treated with .
Background: We compared the tolerability and efficacy of erenumab, a monoclonal antibody binding to the calcitonin gene-related peptide receptor, to topiramate for migraine prophylaxis in adults. Methods: HER-MES was a 24-week, randomised, double-blind, double-dummy, controlled trial conducted in 82 sites in Germany.Basel, November 2, 2020 — Novartis announced today that HER-MES, the first Phase IV, randomized, double-blind, double-dummy, head-to-head study of Aimovig ® (erenumab) against topiramate, an anticonvulsant, in patients with episodic and chronic migraine met its primary and secondary endpoints. HER-MES (NCT03828539) was a 24-week, randomized, double-blind, double-dummy, active-controlled, parallel-group, phase 4 trial conducted in Germany that compared the tolerability and effectiveness of erenumab (70 mg or 140 .
HER-MES is the first randomized, double blind, head-to-head study of Aimovig® (erenumab) against topiramate in patients with episodic and chronic migraine1. KEY CLINICAL TRIAL DETAILS. Patients: Endpoints. Dose: Erenumab administered subcutaneously at a monthly dose of 70 mg or 140 mg significantly reduced migraine frequency, the effects of migraines on daily activities, and the use of acute.The HERMES trial is an international, multicentre, parallel group, randomized, double-blind, study in patients with HFpEF and HFmrEF, evaluating the effect of ziltivekimab 15mg compared with placebo, given once a month, in addition to standard care, on the primary composite outcome of time to first occurrence of cardiovascular death, heart .
Abstract. Background. Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene–related peptide (CGRP), is being investigated as a preventive treatment for migraine. We compared two.Conclusions: HERMES is a global collaboration aiming to (i) identify the genetic determinants of heart failure; (ii) generate insights into the causal pathways leading to heart failure and enable genetic approaches to target prioritization; and (iii) develop genomic tools for disease stratification and risk prediction.Novartis. The HERMeS trial will assess the efficacy of a TM-based follow-up strategy for real-world 'vulnerable phase' HF patients combining telemonitoring and teleintervention. The LIBERTY trial is the first study of a CGRP-targeted therapy in a patient population where multiple preventive treatments had previously failed. Patients treated with Aimovig, reported significant reductions in monthly migraine days and a substantially improved ability to take part in daily activities vs placebo.
Background: We compared the tolerability and efficacy of erenumab, a monoclonal antibody binding to the calcitonin gene-related peptide receptor, to topiramate for migraine prophylaxis in adults. Methods: HER-MES was a 24-week, randomised, double-blind, double-dummy, controlled trial conducted in 82 sites in Germany.Basel, November 2, 2020 — Novartis announced today that HER-MES, the first Phase IV, randomized, double-blind, double-dummy, head-to-head study of Aimovig ® (erenumab) against topiramate, an anticonvulsant, in patients with episodic and chronic migraine met its primary and secondary endpoints. HER-MES (NCT03828539) was a 24-week, randomized, double-blind, double-dummy, active-controlled, parallel-group, phase 4 trial conducted in Germany that compared the tolerability and effectiveness of erenumab (70 mg or 140 .
The genomics of heart failure: design and rationale of the
HER-MES is the first randomized, double blind, head-to-head study of Aimovig® (erenumab) against topiramate in patients with episodic and chronic migraine1. KEY CLINICAL TRIAL DETAILS. Patients: Endpoints. Dose:
Erenumab administered subcutaneously at a monthly dose of 70 mg or 140 mg significantly reduced migraine frequency, the effects of migraines on daily activities, and the use of acute.The HERMES trial is an international, multicentre, parallel group, randomized, double-blind, study in patients with HFpEF and HFmrEF, evaluating the effect of ziltivekimab 15mg compared with placebo, given once a month, in addition to standard care, on the primary composite outcome of time to first occurrence of cardiovascular death, heart . Abstract. Background. Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene–related peptide (CGRP), is being investigated as a preventive treatment for migraine. We compared two.Conclusions: HERMES is a global collaboration aiming to (i) identify the genetic determinants of heart failure; (ii) generate insights into the causal pathways leading to heart failure and enable genetic approaches to target prioritization; and (iii) develop genomic tools for disease stratification and risk prediction.
Novartis. The HERMeS trial will assess the efficacy of a TM-based follow-up strategy for real-world 'vulnerable phase' HF patients combining telemonitoring and teleintervention.
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Study design of Heart failure Events reduction with Remote
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hermes studie novartis|HERMES: Effects Of Ziltivekimab Versus Placebo On Morbidity
